Atif Ali Khan Khalil

Khalil, A.A.K., Woo, M-S, Kang, D-M, Ahn, M-J, Kim J-A, Kim, J-H. Activation of Nuclear Factor Erythroid 2-Related Factor-2 by Oxylipin from Mangifera indica Leaves. Antioxidants. 

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Khalil, A.A.K., Park, W.S., Lee, J., Kim, H.J., Akter, K.M., Goo, Y.M., Bae, J.Y., Chun, M.S., Kim, J.H. and Ahn, M.J., 2019. A new anti-Helicobacter pylori juglone from Reynoutria japonica. Archives of pharmacal research.

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Khalil, A.A.K., Akter, K.M., Kim, H.J., Park, W.S., Kang, D.M., Koo, K.A. and Ahn, M.J., 2020. Comparative inner morphological and chemical studies on Reynoutria species in Korea. Plants.

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Khalil, A.A.K, Qazi, A.S., Nasir, A., Ahn, M.J., Shah, M.A., Ahmad, M.S., Sajjad, W., Ali, T., Naeem, M., Shah, F.A. and Khan, M.T.A., 2022. 2-Methoxy-6-Acetyl-7-Methyljuglone: A Bioactive Phytochemical with Potential Pharmacological Activities. Anti-Cancer Agents in Medicinal Chemistry.

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Khalil, A.A.K., Zeb, F., Khan, R., Shah, S.A., Küpeli Akkol, E., Khan, I.N., Khan, J., Babar Jamal, S., Khuda, F., Haider, A. and Ahmed, S., 2022. An overview on Rumex dentatus L.: Its functions as a source of nutrient and health-promoting plant. Evidence-Based Complementary and Alternative Medicine.

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Khalil, A.A.K., Park, W.S., Kim, H.J., Akter, K.M. and Ahn, M.J., 2016. Anti-Helicobacter pylori compounds from Polygonum cuspidatum. Natural Product Sciences

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Kim, J.H., Khalil, A.A.K., Kim, H.J., Kim, S.E. and Ahn, M.J., 2019. 2-Methoxy-7-acetonyljuglone isolated from Reynoutria japonica increases the activity of nuclear factor erythroid 2-Related factor-2 through inhibition of ubiquitin degradation in HeLa cells. Antioxidants.

 

Akter, K.M., Kim, H.J., Khalil, A.A.K., Park, W.S., Lee, M.K., Park, J.H. and Ahn, M.J., 2018. Inner morphological and chemical differentiation of Boehmeria species. Journal of natural medicines.

 

Kang, D.M., Khalil, A.A.K., Park, W.S., Kim, H.J., Akter, K.M., Bae, J.Y., Mehtap Büyüker, S., Kim, J.H., Kang, K.K. and Ahn, M.J., 2023. Anti-Helicobacter pylori Activity of Six Major Compounds Isolated from Rumex acetosa. ACS omega.

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Khuda, F., Zahir, I., Khalil, A.A.K., Ali, S., Ullah, N., Albariqi, A.H., Ahn, M.J., Shafique, M., Mehtap Büyüker, S. and Almawash, S., 2023. Preparation, characterization, and evaluation of physcion nanoparticles for enhanced oral bioavailability: An attempt to improve its antioxidant and anticancer potential. ACS omega​

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Khuda, F., Gul, M., Khalil, A.A.K., Ali, S., Ullah, N., Shafiq Khan, M., Nazir, S., Irum Khan, S., Mehtap Büyüker, S., Almawash, S. and Shafique, M., 2023. Biosynthesized Silver Nanoparticles Using Alnus nitida Leaf Extract as a Potential Antioxidant and Anticancer Agent. ACS omega

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Bhatti, M.A., Khalil, A.A.K., Bukhari, S.M.A.U.S., Hanif, F., Ahn, M.J., Abbasi, S.W., Lone, N.A., Li, W.J. and Sajjad, W., 2025. Breaking the biofilm barrier: Juglone derivatives as dual-action inhibitors and anti-quorum sensing agents. Phytomedicine Plus

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Niaz, F., Faheem, M., Khattak, M., Khawaja, I.A., Ahn, M.J., Sarker, U., Jamal, S.B., Ullah, R. and Khalil, A.A.K., 2022. Antibacterial and Antibiofilm Activity of Juglone Derivatives against Enterococcus faecalis: An In Silico and In Vitro Approach. BioMed Research International.

 

Shah, I., Uddin, Z., Hussain, M., Khalil, A.A.K., Amin, A., Hanif, F., Ali, L., Amirzada, M.I., Shah, T.A., Dawoud, T.M. and Bourhia, M., 2024. Streptomyces sp. from desert soil as a biofactory for antioxidants with radical scavenging and iron chelating potential. BMC microbiology.

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Ali, A., Nasir, A., Shah, S.W.A., Khalil, A.A.K., Ahn, M.J., Shah, S.M.M., Subhan, F., Faheem, M., Sajjad, W., Shoaib, M. and Ahmad, S., 2021. Evaluation of antinociceptive activity of Ilex dipyrena Wall. in mice. BMC Complementary Medicine and Therapies

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Co-Author Publications

 

Woo, M.S., Khalil, A.A.K., Gonzalez, F.J. and Kim, J.H., 2024. E2F3a activates Gadd45b gene expression through PPARα-mediated transcriptional regulation in hepatic cells. Molecules and Cells​

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Ali, H., Shah, Y., Alnemari, R.M., Khuda, F., Khalil, A.A.K., Alqahtani, A.S., Büyüker, S.M., Ahn, M.J. and Shafique, M., 2024. Preparation and characterization of citreorosein nanoparticles with improved bioavailability and cytotoxic potential. Journal of Saudi Chemical Society

 

Kang, D.M., Kim, H.J., Park, W.S., Bae, J.Y., Akter, K.M., Kim, Y.U., Khalil, A.A.K. and Ahn, M.J., 2023. Antioxidant and Anti-inflammatory Activities of Rumex acetosa. Natural Product Sciences

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Shafiq, A., Abbas, F., Hafeez-ur-Rehman, M., Khan, B.N., Aihetasham, A., Amin, I., Hmidullah, Mothana, R.A., Alharbi, M.S., Khan, I. and Khalil, A.A.K., 2023. Parasite Diversity in a Freshwater Ecosystem. Microorganisms

 

El-Sheikh, M., Mesalam, A.A., Kang, S.M., Joo, M.D., Soliman, S.S., Khalil, A.A.K., Ahn, M.J. and Kong, I.K., 2023. Modulation of apoptosis and autophagy by melatonin in juglone-exposed bovine oocytes. Animals

 

Fatima, M., Amin, A., Alharbi, M., Ishtiaq, S., Sajjad, W., Ahmad, F., Ahmad, S., Faheem, M. and Khalil, A.A.K., 2023. Quorum quenchers from Reynoutria japonica in the battle against methicillin-resistant Staphylococcus aureus (MRSA). Molecules

 

Nasrullah, P.R., Sehar, B., Safdar, M., Fatima, S., Zeb, F., Shah, J., Khalil, A.A.K., Ahmed, B., Alsubaie, A.S.R. and Zaman, M.H., 2023. Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial. Avicenna Journal of Phytomedicine

 

El-Sheikh, M., Mesalam, A., Khalil, A.A.K., Idrees, M., Ahn, M.J., Mesalam, A.A. and Kong, I.K., 2023. Downregulation of PI3K/AKT/mTOR pathway in Juglone-treated bovine oocytes. Antioxidants

 

Khuda, F., Jamil, M., Khalil, A.A.K., Ullah, R., Ullah, N., Naureen, F., Abbas, M., Khan, M.S., Ali, S., Farooqi, H.M.U. and Ahn, M.J., 2022. Assessment of antioxidant and cytotoxic potential of silver nanoparticles synthesized from root extract of Reynoutria japonica Houtt. Arabian Journal of Chemistry

 

Khuda, F., Alam, N., Khalil, A.A.K., Jan, A., Naureen, F., Ullah, Z., Alotaibi, A., Ullah, R., Ullah, S., Shah, Y. and Shah, S.I., 2022. Screening of Rhamnus Purpurea (Edgew.) Leaves for Antimicrobial, Antioxidant, and Cytotoxic Potential. ACS omega

 

Al-Joufi, F.A., Shah, S.W.A., Shoaib, M., Ghias, M., Khalil, A.A.K., Jamal, S.B., Shah, S.M.H. and Zahoor, M., 2022. Flavonoid Derivatives as Potential Cholinesterase Inhibitors in Scopolamine-Induced Amnesic Mice: An In Vitro, In Vivo and Integrated Computational Approach. Brain Sciences

 

Hussain, H., Ahmad, S., Shah, S.W.A., Ullah, A., Ali, N., Almehmadi, M., Ahmad, M., Khalil, A.A.K., Jamal, S.B., Ahmad, H. and Halawi, M., 2022. Attenuation of Scopolamine-Induced Amnesia via Cholinergic Modulation in Mice by Synthetic Curcumin Analogs. Molecules

 

Bari, A., Shah, S.M.M., Al-Joufi, F.A., Shah, S.W.A., Shoaib, M., Shah, I., Zahoor, M., Ahmed, M.N., Ghias, M., Shah, S.M.H. and Khalil, A.A.K., 2022. Effects of Artemisia macrocephala Jacquem on Memory Deficits and Brain Oxidative Stress in Streptozotocin-Induced Diabetic Mice. Molecules

 

Ihsan, M., Nisar, M., Nazir, N., Zahoor, M., Khalil, A.A.K., Ghafoor, A., Khan, A., Mothana, R.A., Ullah, R. and Ahmad, N., 2022. Genetic diversity in nutritional composition of oat (Avena sativa L.) germplasm reported from Pakistan. Saudi journal of biological sciences,

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Ali, A., Nisar, M., Shah, S.W.A., Khalil, A.A.K., Zahoor, M., Nazir, N., Shah, S.A., Nasr, F.A., Noman, O.M., Mothana, R.A. and Ahmad, S., 2022. Anatomical Characterization, HPLC Analysis, and Biological Activities of Ilex dipyrena. Plants, 11(5), p.617.

 

Farooqi, H.M.U., Sammantasinghar, A., Kausar, F., Farooqi, M.A., Chethikkattuveli Salih, A.R., Hyun, K., Lim, J.H., Khalil, A.A.K., Mumtaz, A.S. and Choi, K.H., 2022. Study of the Anticancer Potential of Plant Extracts Using Liver Tumor Microphysiological System. Life

 

Abid, R., Shahzad, M.K., Sulaman, S.M., Faheem, M., Naeem, M., Khan, R., Khalil, A.A.K., Haider, A., Ahmad, B., Gul, R. and Bukhari, N., 2022. Therapeutic significance of nano-and biosensor technology in combating SARS-CoV-2: A review. Applied Nanoscience

 

Oshi, M.A., Haider, A., Siddique, M.I., Zeb, A., Jamal, S.B., Khalil, A.A.K. and Naeem, M., 2022. Nanomaterials for chronic inflammatory diseases: the current status and future prospects. Applied Nanoscience

 

Al-Thomali, A.W., Al-Kuraishy, H.M., Al-Gareeb, A.I., K. Al-buhadiliy, A., De Waard, M., Sabatier, J.M., Khalil, A.A.K., A.A., Saad, H.M. and Batiha, G.E.S., 2022. Role of neuropilin 1 in COVID-19 patients with acute ischemic stroke. Biomedicines

 

Ullah, S., Abid, R., Haider, S., Khuda, F., Albadrani, G.M., Abdulhakim, J.A., Altyar, A.E., Abdel-Daim, M.M., Halimi, S.M.A. and Khalil, A.A.K., 2022. Assessment of tocilizumab (humanized monoclonal antibody) for therapeutic efficacy and clinical safety in patients with coronavirus disease (COVID-19). Medicina

 

Shah, M.A., Haris, M., Faheem, H.I., Hamid, A., Yousaf, R., Rasul, A., Shah, G.M., Khalil, A.A.K, Wahab, A., Khan, H. and Alhasani, R.H., 2022. Cross-talk between obesity and diabetes: introducing polyphenols as an effective phytomedicine to combat the dual sword diabesity. Current Pharmaceutical Design

 

Ahmad, B., Yousafzai, A.M., Khan, W., Rahman, H.U., Almehmadi, M., Halawi, M., Alghamdi, S., Khalil, A.A.K. and Khuda, F., 2022. Evaluation of in-vitro and in-vivo antimicrobial potential of Typha elephantina leaves extracts using Cyprinus carpio as a research model. Pak. J. Pharm. Sci

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Kausar, F., Kim, K.H., Farooqi, H.M.U., Farooqi, M.A., Kaleem, M., Waqar, R., Khalil, A.A.K., Khuda, F., Abdul Rahim, C.S., Hyun, K. and Choi, K.H., 2021. Evaluation of Antimicrobial and Anticancer Activities of Selected Medicinal Plants of Himalayas, Pakistan. Plants, 

 

Ali, A., Nasir, A., Shah, S.W.A., Khalil, A.A.K., Ahn, M.J., Shah, S.M.M., Subhan, F., Faheem, M., Sajjad, W., Shoaib, M. and Ahmad, S., 2021. Evaluation of antinociceptive activity of Ilex dipyrena Wall. in mice. BMC Complementary Medicine and Therapies

 

Park, W.S., Kim, H.J., Khalil, A.A.K., Kang, D.M., Akter, K.M., Kwon, J.M., Kim, Y.U., Piao, X.L., Koo, K.A. and Ahn, M.J., 2021. Anatomical and Chemical Characterization of Ulmus Species from South Korea. Plants

 

Khuda, F., Haq, Z.U., Ilahi, I., Ullah, R., Khan, A., Fouad, H., Khalil, A.A.K., Ullah, Z., Sahibzada, M.U.K., Shah, Y. and Abbas, M., 2021. Synthesis of gold nanoparticles using Sambucus wightiana extract and investigation of its antimicrobial, anti-inflammatory, antioxidant and analgesic activities. Arabian Journal of Chemistry

 

Shahzad, S., Ullah, S., Nazar, Z., Riaz, M., Khuda, F., Khalil, A.A.K., Almutairi, M.H., Sayed, A.A., Büyüker, S.M. and Khan, N., 2022. Assessment of contributing factors and treatment practices for therapeutic efficacy and drug-related problems in suicidal psychotic patients. Brain sciences

 

Alharbi, M., Alshammari, A., Alasmari, A.F., Alharbi, S.M., Tahir ul Qamar, M., Ullah, A., Ahmad, S., Irfan, M. and Khalil, A.A.K., 2022. Designing of a recombinant multi-epitopes based vaccine against Enterococcus mundtii using bioinformatics and immunoinformatics approaches. International journal of environmental research and public health, 

 

Alam, I., Ullah, R., Jan, A., Sehar, B., Khalil, A.A.K., Naqeeb, H., Ali, E.A., Wahab, Q.M.F., Safdar, M., Ali, A. and Zaman, M.H., 2022. Improvement in cardio-metabolic health and immune signatures in old individuals using daily chores (Salat) as an intervention: a randomized crossover study in a little-studied population. Frontiers in Public Health

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Aslam, F., Kanwal, T., Shah, M.R., Khalil, A.A.K., Shah, S.W.A., Alshammari, E.M., El-Masry, E.A. and Batiha, G.E., 2021. Enhanced antibacterial potential of amoxicillin against Helicobacter pylori mediated by lactobionic acid coated Zn-MOFs. Antibiotics, .

 

Abidin, S.Z.U., Munem, A., Khan, R., Batiha, G.E.S., Amhad, M., Zafar, M., Khalil, A.A.K., Hetta, H.F., Mahmoud, M.H., Sami, A. and Bhatti, M.Z., 2021. Ethnoveterinary botanical survey of medicinal plants used in Pashto, Punjabi and Saraiki communities of Southwest Pakistan. Veterinary Medicine and Science

 

Riasat, I., Bakhtiar, S.M., Faheem, M., Jaiswal, A.K., Naeem, M., Khan, R., Khan, A.U., Khalil, A.A.K., Haider, A., Junaid, M. and de Castro Soares, S., 2021. Application of pan genomics towards the druggability of Clostridium botulinum. Applied Nanoscience

 

Ahmad, B., Ilahi, I., Yousafzai, A.M., Attaullah, M., Rahim, A., Naz, D., Hazrat, A., Batiha, G., Nassan, M.A. and Khalil, A.A.K., 2021. Protective effects of Zizyphus oxyphyla on liver and kidney related serum biomarkers in (CCl4) intoxicate rabbits. Brazilian Journal of Biology

 

Ihsan, M., Nazir, N., Ghafoor, A., Khalil, A.A.K., Zahoor, M., Nisar, M., Khames, A., Ullah, R. and Shah, A.B., 2021. Genetic Diversity in Local and Exotic Avena sativa L.(Oat) Germplasm Using Multivariate Analysis. Agronomy.

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Ali, A., Khalil, A.A.K., Khuda, F., Nazir, N., Ullah, R., Bari, A., Haider, A., Jamal, S.B., Ahmad, S., Khan, Z. and Shah, S.M.M., 2021. Phytochemical and Biological Screening of Leaf, Bark and Fruit Extracts from Ilex dipyrena Wall. Life

 

Khan, J., Majid, A., Nazir, N., Nisar, M., Khalil, A.A.K, Zahoor, M., Ihsan, M., Ullah, R., Bari, A. and Shah, A.B., 2021. HPLC Characterization of Phytochemicals and Antioxidant Potential of Alnus nitida (Spach) Endl. Horticulturae

 

Kausar, F., Farooqi, M.A., Farooqi, H.M.U., Salih, A.R.C., Khalil, A.A.K., Kang, C.W., Mahmoud, M.H., Batiha, G.E.S., Choi, K.H. and Mumtaz, A.S., 2021. Phytochemical Investigation, Antimicrobial, Antioxidant and Anticancer Activities of Acer cappadocicum Gled. Life

 

Khan, J., Ali, G., Rashid, U., Khan, R., Jan, M.S., Ullah, R., Ahmad, S., Abbasi, S.W., Khalil, A.A.K. and Sewell, R.E., 2021. Mechanistic evaluation of a novel cyclohexenone derivative’s functionality against nociception and inflammation: an in-vitro, in-vivo and in-silico approach. European Journal of Pharmacology

 

Begum, N., Nasir, A., Parveen, Z., Muhammad, T., Ahmed, A., Farman, S., Jamila, N., Shah, M., Bibi, N.S., Khurshid, A. and Huma, Z., Khalil, A.A.K., 2021. Evaluation of the hypoglycemic activity of Morchella conica by targeting protein tyrosine phosphatase 1B. Frontiers in pharmacology,

 

Ilahi, I., Khuda, F., Sahibzada, M.U.K., Alghamdi, S., Ullah, R., Dablool, A.S., Alam, M., Khan, A. and Khalil, A.A.K., 2021. Synthesis of silver nanoparticles using root extract of Duchesnea indica and assessment of its biological activities. Arabian Journal of Chemistry

 

Nasir, A., Khalil, A.A.K, Bhatti, M.Z., Ur Rehman, A., Li, J. and Parveen, Z., 2021. Review on Pharmacological and Phytochemical Prospects of Traditional Medicinal Plant: Persicaria hydropiper (Smartweed). Current Topics in Medicinal Chemistry.

 

Rahman, Z.U., Al Kury, L.T., Alattar, A., Tan, Z., Alshaman, R., Malik, I., Badshah, H., Uddin, Z., Khalil, A.A.K, Muhammad, N. and Khan, S., 2021. Carveol a naturally-derived potent and emerging Nrf2 activator protects against acetaminophen-induced hepatotoxicity. Frontiers in Pharmacology

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Nasir, A., Khan, A., Li, J., Naeem, M., Khalil, A.A.K, and Qasim, M., 2021. Nanotechnology, a tool for diagnostics and treatment of cancer. Current topics in medicinal chemistry

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Shams, S., Imran, N., Afridi, S.G., Ayaz, M., Khalil, A.A.K. and Nasir, A., 2021. In vitro differentiation effect of CCL 4-induced liver injured mice serum on bone marrow-derived mesenchymal stem cells toward hepatocytes like cells. Cell and Tissue Banking

 

Nazir, N., Rahman, A., Uddin, F., Khalil, A.A.K, Zahoor, M., Nisar, M., Ullah, S., Ullah, R., Ezzeldin, E. and Mostafa, G.A., 2021. Quantitative ethnomedicinal status and phytochemical analysis of Berberis lyceum Royle. Agronomy

 

Mesalam, A.A., El-Sheikh, M., Joo, M.D., Khalil, A.A.K., Mesalam, A., Ahn, M.J. and Kong, I.K., 2020. Induction of oxidative stress and mitochondrial dysfunction by juglone affects the development of bovine oocytes. International Journal of Molecular Sciences

 

Khan, A., Muhamad, N.A., Ismail, H., Nasir, A., Khalil, A.A.K., Anwar, Y., Khan, Z., Ali, A., Taha, R.M., Al-Shara, B. and Latif, S., 2020. Potential nutraceutical benefits of in vivo grown saffron (Crocus sativus L.) as analgesic, anti-inflammatory, anticoagulant, and antidepressant in mice. Plants

 

Nazir, N., Khalil, A.A.K., Nisar, M., Zahoor, M. and Ahmad, S., 2020. HPLC-UV characterization, anticholinesterase, and free radical-scavenging activities of Rosa moschata Herrm. leaves and fruits methanolic extracts. Brazilian Journal of Botany

 

Nasir, A., Khan, M., Rehman, Z., Khalil, A.A.K., Farman, S., Begum, N., Irfan, M., Sajjad, W. and Parveen, Z., 2020. Evaluation of Alpha-Amylase Inhibitory, Antioxidant, and Antimicrobial Potential and Phytochemical Contents of Polygonum hydropiper L. Plants, 

 

Al Kury, L.T., Dayyan, F., Ali Shah, F., Malik, Z., Khalil, A.A.K., Alattar, A., Alshaman, R., Ali, A. and Khan, Z., 2020. Ginkgo biloba extract protects against methotrexate-induced hepatotoxicity: a computational and pharmacological approach. Molecules

 

Akter, K.M., Park, W.S., Kim, H.J., Khalil, A.A.K. and Ahn, M.J., 2020. Comparative studies of fraxinus species from korea using microscopic characterization, phytochemical analysis, and anti-lipase enzyme activity. Plants

 

Park, W.S., Kim, H.J., Choe, S.J., Khalil, A.A.K., Akter, K.M., Shin, M.C., Chung, H.J., Park, J.H. and Ahn, M.J., 2020. Anatomical characterization and LC-MS profiling of Adenophora roots from Korea. Revista Brasileira de Farmacognosia

 

Akter, K.M., Kim, H.J., Park, W.S., Khalil, A.A.K. and Ahn, M.J., 2020. Anti-Helicobacter pylori activity of compounds isolated from Fraxinus mandshurica bark. Natural Product Sciences

 

Al Kury, L.T., Zeb, A., Abidin, Z.U., Irshad, N., Malik, I., Alvi, A.M., Khalil, A.A.K., Ahmad, S., Faheem, M., Khan, A.U. and Shah, F.A., 2019. Neuroprotective effects of melatonin and celecoxib against ethanol-induced neurodegeneration: a computational and pharmacological approach. Drug design, development and therapy

 

Khan, I., Chowdhury, M.M.R., Song, S.H., Mesalam, A., Zhang, S., Khalil, A.A.K., Jung, E.H., Kim, J.B., Jafri, L., Mirza, B. and Kong, I.K., 2018. Lupeol supplementation improves the developmental competence of bovine embryos in vitro. Theriogenology